New compound found to inhibit one type of tumor in animals.pdf

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extracted text: possessed of the higest spirit ual values common to all mankind. Being a young na tion we cannot expect fullest maturity and ripest judgment in our conduct as a people. It is enough that we have the dynamism of youth and a new outlook. By the new outlook I mean that we must as a people, individually and * collectively, be possessed first of the highest intellectual and moral values before we can be possessor of our lands. To do otherwise is to repeat our history. Let us see if the youth can be better than the old in the possession of the new outlook and the new vi sion of a greater and happier Philippines. ♦ * NEW COMPOUND FOUND TO INHIBIT ONE TYPE OF TUMOR IN ANIMALS A new compound which in animal experi ments inhibits one type of tumor by 90 to 100 per cent has been fashioned from a potential cancer drug now undergoing clinical tests in the United States. The chemical, a piperazine derivative la belled A-20968, is effective against Carcinoma 755, a transplantable mouse tumor, and also shows activity against two common types of can cer, Sarcoma 180 and Leukemia 1210, according to Dr. John A. Carbon, a research chemist at Ab bott Laboratories, North Chicago, Illinois. The new compound has not yet been tried on human beings. The model for the compound was called A-8103, and it represents an entirely new type of. chemical structure to show activity against tumors, Dr. Carbon said, adding: “Although it is probably a member of the class of anti-tumor agents known as ‘alkylating agents,’ it possesses a chemical structure of an entirely different type from the known com pounds of this class. It thus offers an opportunity or ‘lead’ for the organic chemist to synthesize many closely related compounds as possible tu mor growth inhibitors.” October 1961 53
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